
What you want more of
Balanced energy and hormonal health
Steadier energy, a clearer head, and a body that recovers — whoever you are.
Does this sound like you?
- 01
You've handled every hard thing life has ever sent you. Why does this one — your own body, changing — feel like it's happening to you?
- 02
You have the best physicians money can buy. Why does it feel like no one is treating the whole of what you're experiencing?
- 03
The energy, the edge, the drive — you didn't decide to give them up. So why does everyone act like it's just age?
- 04
You could buy the testosterone shot tomorrow. What if it's treating the symptom and missing the cause entirely?
(002) What the evidence says
Every claim links to a primary or authoritative source.
Perimenopause is driven by the ovaries producing less estrogen, which destabilizes the hormonal balance and sets off symptoms like hot flashes, mood swings, and disrupted sleep — a transition that lasts about four years on average and up to eight.
Cleveland ClinicSleep is one of the hardest-hit systems: sleep disorders affect an estimated 16 to 47 percent of women in perimenopause and 35 to 60 percent after menopause, and hot flashes and disrupted sleep feed each other in a two-way loop.
Journal of Clinical Medicine (peer-reviewed narrative review, 2025)In a randomized controlled trial, women who learned mindfulness-based stress reduction reported meaningfully less bother from hot flashes and night sweats, along with statistically significant gains in sleep quality, anxiety, perceived stress, and quality of life that held three months later.
Menopause (journal of The Menopause Society) / PubMedA review of the evidence links time in natural settings to better mental health and, in many studies, to lower cortisol — the body's main stress hormone. Chronic stress is one of the quiet drivers that turns a man's hormones down.
NIH / PubMed Central reviewAcross 17 randomized trials, regular physical activity was associated with reduced depressive symptoms in menopausal women — a meaningful, drug-free lever for the mood side of the transition.
Frontiers in Psychiatry (systematic review and meta-analysis, 2025)One week of sleeping only about 5 hours a night dropped healthy young men's daytime testosterone by 10 to 15 percent — since testosterone normally falls only 1 to 2 percent a year with age, that single week undid years of decline. Rest isn't a luxury for men's vitality; it's a lever.
JAMAWhen low testosterone comes from carrying extra weight, it's usually not permanent. Reviews of the research find that substantial weight loss reactivates the body's own testosterone system, with the rise roughly in proportion to the weight lost.
PubMed Central (Asian Journal of Andrology review)In older adults, supervised strength training reliably improves muscle strength, walking speed, and everyday physical function while lowering body-fat mass — the practical markers of feeling strong again, without any medication.
PubMed Central (systematic review & meta-analysis)Pooling 70 studies of more than 3 million people, researchers found weak social ties raise the risk of early death by roughly 26 to 32 percent — a factor as serious as many we treat medically, and one that hits midlife men especially hard.
Perspectives on Psychological Science (Holt-Lunstad et al.)
Santerra is not a medical facility and does not diagnose or treat disease. The week is built to move the inputs your own physician measures.
(003) The mechanisms your week is built on
Each of these sits behind a specific slot on your itinerary, grouped by how strong the evidence is. Where the honest answer is we think so, and we are measuring it, the page says so rather than dressing it up.
StrongMeta-analysis, a replicated body of trials, or a large prospective cohort.
Morning light advances circadian phase and consolidates sleep timing
Wright et al., Current Biology, 2013Cutaneous vitamin D synthesis from UVB exposure
Holick, New England Journal of Medicine, 2007Social relationships and survival: 148 studies, 308,849 participants
Holt-Lunstad et al., PLoS Medicine, 2010Expressive writing and measurable health outcomes
Pennebaker & Beall, J. Abnormal Psychology, 1986Nature experience reduces rumination and subgenual prefrontal activation
Bratman et al., PNAS, 2015Dietary fibre and whole grains: mortality and chronic disease
Reynolds et al., The Lancet, 2019Frequent sauna bathing and cardiovascular and all-cause mortality
Laukkanen et al., JAMA Internal Medicine, 2015Short post-meal walking attenuates postprandial glucose
Buffey et al., Sports Medicine, 2022Racquet sports and social exercise: leisure activity and mortality
Oja et al., British J. Sports Medicine, 2017Mindfulness meditation for anxiety, depression and pain (effect ~0.3)
Goyal et al., JAMA Internal Medicine, 2014Awe elicits the small self and increases prosocial behavior
Piff et al., J. Personality & Social Psychology, 2015Evening light exposure suppresses melatonin and delays circadian phase
Gooley et al., J. Clinical Endocrinology & Metabolism, 2011Muscle-strengthening activity and all-cause mortality
Momma et al., British J. Sports Medicine, 2022Cardiorespiratory fitness and long-term mortality: no observed ceiling
Mandsager et al., JAMA Network Open, 2018
EmergingReal evidence, still thin — a single trial or a small literature.
Cyclic sighing improves mood and lowers respiratory rate
Balban et al., Cell Reports Medicine, 2023
“The goal isn't to push through the change. It's to move through it — steadier, rested, and able to prove what shifted.”
(004) How Santerra drives it
The method, aimed at this
Three phases. Most programs run only the middle one.
[PHASE 1]
Preparation
Before arrival, every guest completes a flourishing assessment across body, mind, and spirit and names one intention for the week — so the transition isn't treated as a vague complaint but as a specific starting point we can measure against. This baseline, paired with wearable data, is what makes the day-90 comparison honest rather than aspirational.
[PHASE 2]
Immersion
Over five nights at Santerra, you practice the exact drug-free levers the evidence supports: guided mindfulness and stress-reduction work shown to ease hot-flash bother and improve sleep, daily movement in nature, and a full protected rest day to let an over-taxed nervous system actually come down. The forgiveness and purpose sessions do the deeper work — releasing what's been carried and reconnecting to meaning, which research ties to better long-term health.
[PHASE 3]
Reinforcement
The week is the beginning, not the finish. For 90 days you get group coaching with your cohort and a small community of women in the same season of life — sustained connection that helps the sleep, mood, and stress gains hold. At day 90 we re-measure, so the changes are something you can see, not just hope for.
(005) Why we suggest what we suggest
Four of the afternoon choices earn their place on this track in particular. These are what your own day-sheets actually schedule — a nudge, never a default.
Gym or personal training
Loading is the lever on this track, and the week builds toward a weighted canyon hike.
Momma et al., British J. Sports Medicine, 2022Pickleball
Lateral movement, a teammate who depends on you, and nobody keeping a season record.
Oja et al., British J. Sports Medicine, 2017A second guided hike
Foraging and harvest walks with the herbalist — you choose and cut what goes on the table tonight.
Bratman et al., PNAS, 2015Activity trail and mud baths
The activity trail on the bajada, at whatever pace the day allows, and the mud baths at the end of it.
Mandsager et al., JAMA Network Open, 2018
(006) And then we measure it
At day 90 we re-measure each guest's flourishing scores — with particular attention to the mental and physical health domains — alongside wearable deltas in sleep quality, resting heart rate, and heart-rate variability, the markers most likely to shift when a stressed midlife nervous system finally gets to recover.
Day ninety is the one that counts — anyone can feel better on the drive home. You leave with your results in a form you can share with your own physician.
This is the week you've been waiting for
Reservations are not yet open — the invitation list hears first.